ACE inhibitors in renal disease
نویسندگان
چکیده
منابع مشابه
ACE inhibitors and appearance of renal events in hypertensive nephrosclerosis.
Nephrosclerosis constitutes a major cause of end-stage renal disease. Independently of blood pressure control, ACE inhibitors (ACEIs) are considered to be more nephroprotective than other antihypertensive agents. We have reviewed the long-term evolution of renal function in our series of essential hypertensive patients diagnosed as having nephrosclerosis when first seen in our unit. The analysi...
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The success of Angiotensin-converting enzyme (ACE) inhibitors in preventing the progression of chronic renal insufficiency has led investigators to study the effects of other inhibitors of the renin-angiotensin system (RAS). Recently, the results of the first large-scale trials with angiotensin II type 1 receptor (AT1) antagonists became available (1,2). This article discusses the relative meri...
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We examined the renal responsiveness to ACE inhibitor in IgA nephropathy (IgAN) patients according to the grouping of ACE gene polymorphism. Sixty one patients diagnosed as IgAN by renal biopsy and prescribed with ACE inhibitors were enrolled. Genomic DNA was extracted from whole blood and PCR was performed. The I/D polymorphism was determined by the presence of the 287 bp fragment in intron 16...
متن کاملAssociation studies, ACE polymorphisms and renal disease.
The genetic contribution to major disorders is increasingly recognized. This usually reflects interaction at a number of different loci to determine the eventual clinical phenotype, and dissecting out the role of individual components is a complex task. However, a clear understanding of the genetic factors involved in diseases such as hypertension, atherosclerosis, diabetes and glomerulonephrit...
متن کاملAtherosclerotic renal artery stenosis, ACE inhibitors, and avoiding cardiovascular death.
Correspondence to: Dr John Main, Renal Unit, James Cook University Hospital, Marton Road, Middlesbrough TS4 3BW, UK; [email protected] _________________________ A therosclerotic renal artery stenosis (ARAS) has become topical since the development of percutaneous angioplasty and stenting. Studies defining the place for intervention have been difficult to perform and inconclusive. However, ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1992
ISSN: 0085-2538
DOI: 10.1038/ki.1992.311